Abstract | OBJECTIVE: STUDY DESIGN: Between 1987 and 2005, fetal blood samples were taken at the first fetal blood transfusion in 224 Rh-D alloimmunized pregnancies. We measured hemoglobin concentration and albumin concentration and assessed the severity of hydrops. RESULTS: A decrease in albumin concentration occurred only below a hemoglobin deficit of >8 SDs in 27 fetuses. In 161 nonhydropic, 44 mildly hydropic, and 19 severely hydropic fetuses, albumin concentrations were >2 SDs below the mean for gestational age in 6%, 14%, and 63%, respectively. CONCLUSION: Our finding that most fetuses with immune hydrops have an albumin concentration within the normal range (71%) suggests that hypoalbuminemia is unlikely to cause the initial development of immune hydrops.
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Authors | Suzanne A Pasman, Robertjan H Meerman, Frank P H A Vandenbussche, Dick Oepkes |
Journal | American journal of obstetrics and gynecology
(Am J Obstet Gynecol)
Vol. 194
Issue 4
Pg. 972-5
(Apr 2006)
ISSN: 1097-6868 [Electronic] United States |
PMID | 16580285
(Publication Type: Journal Article)
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Topics |
- Humans
- Hydrops Fetalis
(etiology)
- Hypoalbuminemia
(complications)
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