Middle lobe syndrome as the pulmonary manifestation of primary Sjögren's syndrome.

Abstract

Middle lobe syndrome - recurrent atelectasis and/or bronchiectasis involving the right middle lobe and/or lingula - has, up to now, not been reported as the pulmonary manifestation of primary Sjögren's syndrome. We describe a patient in whom lymphocytic bronchiolitis in the atelectatic lobes was proved histologically from two separate transbronchial biopsies. The atelectasis responded well to glucocorticoid treatment, suggesting that the peribronchiolar lymphocytic infiltrates may have played an important role in the development of middle lobe syndrome in this patient.

• Authors: Horng-An Chen, Shinn-Liang Lai, Wei-Kang Kwang, Juhn-Cherng Liu, Chun-Hsiung Chen, De-Feng Huang
• Journal: The Medical journal of Australia (Med J Aust) Vol. 184 Issue 6 Pg. 294-5 (Mar 20 2006) ISSN: 0025-729X [Print] Australia
• PMID: 16548837 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Prednisolone

Topics

• Female
• Glucocorticoids (therapeutic use)
• Humans
• Lung (diagnostic imaging, pathology)
• Middle Aged
• Middle Lobe Syndrome (diagnosis, drug therapy, etiology)
• Prednisolone (therapeutic use)
• Radiography
• Recurrence
• Sjogren's Syndrome (complications)
• Treatment Outcome