Abstract | OBJECTIVE: To assess clinical benefit of portal vein embolization (PVE) before extended, complex hepatectomy for biliary cancer. SUMMARY BACKGROUND DATA: METHODS: This study involved 240 consecutive patients with biliary cancer (150 cholangiocarcinomas and 90 gallbladder cancers) who underwent PVE before an extended hepatectomy (right or left trisectionectomy or right hepatectomy). All PVEs were performed by the "ipsilateral approach" 2 to 3 weeks before surgery. Hepatic volume and function changes after PVE were analyzed, and the outcome also was reviewed. RESULTS: CONCLUSIONS: PVE has the potential benefit for patients with advanced biliary cancer who are to undergo extended, complex hepatectomy. Along with the use of PVE, further improvements in surgical techniques and refinements in perioperative management are necessary to make difficult hepatobiliary resections safer.
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Authors | Masato Nagino, Junichi Kamiya, Hideki Nishio, Tomoki Ebata, Toshiyuki Arai, Yuji Nimura |
Journal | Annals of surgery
(Ann Surg)
Vol. 243
Issue 3
Pg. 364-72
(Mar 2006)
ISSN: 0003-4932 [Print] United States |
PMID | 16495702
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Bile Duct Neoplasms
(blood supply, mortality, therapy)
- Bile Ducts, Intrahepatic
- Cholangiocarcinoma
(blood supply, mortality, therapy)
- Embolization, Therapeutic
(methods, statistics & numerical data)
- Female
- Follow-Up Studies
- Gallbladder Neoplasms
(blood supply, mortality, therapy)
- Hepatectomy
(methods)
- Humans
- Male
- Middle Aged
- Portal Vein
- Preoperative Care
(methods, statistics & numerical data)
- Retrospective Studies
- Survival Rate
- Time Factors
- Treatment Outcome
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