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A phase I study of a DNA vaccine targeting prostatic Acid phosphatase in patients with stage D0 prostate cancer.

AuthorsSarah Zlotocha, Mary Jane Staab, Dorothy Horvath, Jane Straus, Jeanne Dobratz, Katherine Oliver, Stephine Wasielewski, Dona Alberti, Glenn Liu, George Wilding, Jens Eickhoff, Douglas G McNeel
JournalClinical genitourinary cancer (Clin Genitourin Cancer) Vol. 4 Issue 3 Pg. 215-8 (Dec 2005) ISSN: 1558-7673 [Print] United States
PMID16425992 (Publication Type: Clinical Trial, Phase I, Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S.)
Chemical References
  • Adjuvants, Immunologic
  • Interferon-alpha
  • Vaccines, DNA
  • Granulocyte-Macrophage Colony-Stimulating Factor
  • Acid Phosphatase
  • prostatic acid phosphatase
  • Protein Tyrosine Phosphatases
Topics
  • Acid Phosphatase
  • Adenocarcinoma (immunology, pathology, therapy)
  • Adjuvants, Immunologic (therapeutic use)
  • CD8-Positive T-Lymphocytes (immunology)
  • Granulocyte-Macrophage Colony-Stimulating Factor (immunology, therapeutic use)
  • Humans
  • Interferon-alpha (biosynthesis)
  • Male
  • Neoplasm Staging
  • Prostatic Neoplasms (immunology, pathology, therapy)
  • Protein Tyrosine Phosphatases (antagonists & inhibitors)
  • Treatment Outcome
  • Vaccines, DNA (immunology, therapeutic use)

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