Laparoscopic nephroureterectomy for upper tract transitional cell carcinoma: comparison of laparoscopic and open surgery.

Abstract

OBJECTIVES:

We made a comparative study of laparoscopic nephroureterectomy (LNU) and standard open surgery (ONU) for upper urinary tract transitional cell carcinoma.

METHODS AND METHODS:

From July 2000 to February 2005, 49 patients underwent total nephroureterectomy for upper tract transitional cell carcinoma at Osaka University Medical Hospital. Of the 49 patients, twenty-five were treated with LNU, and twenty-four with ONU. Each group of cases was reviewed with respect to operative time, complications and postoperative convalescence.

RESULTS:

The average operative time of the LNU and ONU group was 305.9 min (range 190-480) and 271.2 min (range 135-480) respectively, and the average blood loss was 321.5 ml (80-1370) and 557.7 ml (range 100-1730), respectively. The average time until ambulation after LNU and ONU was 2.2 days (range 1-3) and 4.0 days (range 3-5), respectively. No major postoperative complications were observed in either group.

CONCLUSION:

ONU still represents the gold standard for the management of upper tract transitional cell carcinoma; however, for low stage cases, LNU offers the advantages of minimally invasive surgery.

• Authors: Masao Tsujihata, Norio Nonomura, Akira Tsujimura, Kazuhiro Yoshimura, Yasushi Miyagawa, Akihiko Okuyama
• Journal: European urology (Eur Urol) Vol. 49 Issue 2 Pg. 332-6 (Feb 2006) ISSN: 0302-2838 [Print] Switzerland
• PMID: 16387415 (Publication Type: Comparative Study, Journal Article)

Topics

• Adult
• Aged
• Aged, 80 and over
• Carcinoma, Transitional Cell (mortality, pathology, surgery)
• Female
• Follow-Up Studies
• Humans
• Laparoscopy
• Male
• Middle Aged
• Neoplasm Staging
• Nephrectomy (methods)
• Nephrons (pathology, surgery)
• Perioperative Care
• Prognosis
• Survival Analysis
• Time Factors
• Treatment Outcome
• Ureter (pathology, surgery)
• Urologic Neoplasms (mortality, pathology, surgery)