[Study on the structure of periodic and chaotic patterns of AMP-DC-Cu-gel systems].

Abstract

This is an in vitro model to mimic the conditions present during gallstone formation. Adenosine mono-phosphate (AMP), an important bio-molecule, was chosen. Its effect on the formation of periodic/chaotic patterns in the deoxycholate-CuCl2-gel and deoxycholate-CuCl2-glucose-gel systems were studied. FTIR spectroscopy was used to identify the structure of the precipitates. The results indicate that the patterns formed in the systems with AMP are different. And FTIR spectra show that AMP may also be involved in the coordination sphere of Cu2+ ion. The results are more complicated in the deoxycholate-CuCl2 system containing glucose, suggesting that the nonlinear scientific concept should be considered in understanding gallstone formation.

• Authors: Wen-xuan Yin, Yu-feng Liu, Ying Zhao, Qing-yu Gao, Jin-guang Wu
• Journal: Guang pu xue yu guang pu fen xi = Guang pu (Guang Pu Xue Yu Guang Pu Fen Xi) Vol. 25 Issue 6 Pg. 930-3 (Jun 2005) ISSN: 1000-0593 [Print] China
• PMID: 16201375 (Publication Type: Journal Article)

Chemical References

• Gels
• Deoxycholic Acid
• Adenosine Monophosphate
• Copper
• cupric chloride

Topics

• Adenosine Monophosphate (chemistry)
• Copper (chemistry)
• Deoxycholic Acid (chemistry)
• Gallstones (chemistry, pathology)
• Gels (chemistry)
• Humans
• Models, Anatomic
• Molecular Structure
• Spectroscopy, Fourier Transform Infrared