Studies on pathological morphology, clinical features and nuclear DNA contents by flow cytometry in adrenal neoplasms.

Abstract

Pathological morphology, clinical features and nuclear DNA contents determined by flow cytometry (FCM) were studied in 11 cases of normal adrenals and 41 cases of adrenal neoplasms. It was found that despite differences in clinical manifestations and in degrees of cellular atypia of the adenomas their DNA contents were the same as in normal adrenals. On the other hand, the pheochromocytomas were benign in nature, but most of them (16/19) showed DNA aneuploidy and the DNA indices were correlated with their clinical and morphological features.

• Authors: X H Zhang, S L Wei, F R Wang, J L Wang, T X Xie, D W Liu, L F Zuo, J W Guo
• Journal: Chinese medical journal (Chin Med J (Engl)) Vol. 105 Issue 2 Pg. 139-43 (Feb 1992) ISSN: 0366-6999 [Print] China
• PMID: 1597074 (Publication Type: Journal Article)

Chemical References

• DNA, Neoplasm

Topics

• Adenoma (pathology)
• Adrenal Cortex Neoplasms (pathology)
• Adrenal Gland Neoplasms (pathology)
• Aneuploidy
• DNA, Neoplasm (analysis)
• Flow Cytometry
• Humans
• Pheochromocytoma (pathology)