Abstract | PURPOSE: MATERIALS AND METHODS: We report 13 novel cases of desmopressin associated water intoxication and review the literature. A total of 93 instances of symptomatic hyponatremia during desmopressin treatment in children were identified. Specific data were reported in 58 of 93 cases. These 58 cases, in addition to our 13 novel cases, were further analyzed. RESULTS: CONCLUSIONS: Based on this analysis, we conclude that the use of desmopressin should be cautiously considered, careful monitoring should be performed during the initiation of therapy, and particular care should be taken when treating young children and when prodromal symptoms such as nausea, vomiting and headaches occur.
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Authors | Julia Thumfart, Charles-Christoph Roehr, Klaus Kapelari, Uwe Querfeld, Paul Eggert, Dominik Müller |
Journal | The Journal of urology
(J Urol)
Vol. 174
Issue 1
Pg. 294-8; discussion 298
(Jul 2005)
ISSN: 0022-5347 [Print] United States |
PMID | 15947670
(Publication Type: Journal Article, Review)
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Chemical References |
- Renal Agents
- Deamino Arginine Vasopressin
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Topics |
- Adolescent
- Child
- Child, Preschool
- Deamino Arginine Vasopressin
(adverse effects)
- Female
- Humans
- Hyponatremia
(chemically induced)
- Hypovolemia
(chemically induced)
- Male
- Renal Agents
(adverse effects)
- Water Intoxication
(chemically induced)
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