Abstract | BACKGROUND AND AIM: The influence of Helicobacter pylori on gastric acid secretion differs with the status of gastritis. The histological characteristics of gastritis in H. pylori-positive patients with reflux esophagitis have not been fully investigated. We therefore studied the pattern of endoscopic gastric mucosal atrophy and degree of histological gastritis in such patients. METHODS: Subjects comprised 41 H. pylori-positive patients with reflux esophagitis, 41 age- and sex-matched patients with duodenal ulcer, and 41 patients with early gastric cancer. The endoscopic pattern of gastric mucosal atrophy was reviewed, and the degree of histological gastritis in biopsy specimens from the antrum and corpus was assessed in accordance with the updated Sydney system. RESULTS: CONCLUSION:
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Authors | Takafumi Mihara, Kyoichi Adachi, Yoshinori Komazawa, Manabu Yoshida, Asuka Araki, Riruke Maruyama, Kenji Furuta, Shunji Ishihara, Yuji Amano, Yoshikazu Kinoshita |
Journal | Journal of gastroenterology and hepatology
(J Gastroenterol Hepatol)
Vol. 20
Issue 5
Pg. 682-7
(May 2005)
ISSN: 0815-9319 [Print] Australia |
PMID | 15853979
(Publication Type: Journal Article)
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Topics |
- Case-Control Studies
- Duodenal Ulcer
(pathology)
- Esophagitis, Peptic
(pathology)
- Female
- Gastric Mucosa
(pathology)
- Gastritis, Atrophic
(microbiology, pathology)
- Helicobacter Infections
(pathology)
- Helicobacter pylori
- Hernia, Hiatal
(pathology)
- Humans
- Male
- Middle Aged
- Pyloric Antrum
(pathology)
- Severity of Illness Index
- Stomach Neoplasms
(pathology)
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