Malaria epidemic and drug resistance, Djibouti.

Abstract

Analysis of Plasmodium falciparum isolates collected before, during, and after a 1999 malaria epidemic in Djibouti shows that, despite a high prevalence of resistance to chloroquine, the epidemic cannot be attributed to a sudden increase in drug resistance of local parasite populations.

• Authors: Christophe Rogier, Bruno Pradines, H Bogreau, Jean-Louis Koeck, Mohamed-Ali Kamil, Odile Mercereau-Puijalon
• Journal: Emerging infectious diseases (Emerg Infect Dis) Vol. 11 Issue 2 Pg. 317-21 (Feb 2005) ISSN: 1080-6040 [Print] United States
• PMID: 15752455 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antimalarials
• DNA, Protozoan

Topics

• Animals
• Antimalarials (therapeutic use)
• DNA, Protozoan (chemistry, genetics)
• Disease Outbreaks
• Djibouti (epidemiology)
• Drug Resistance (genetics)
• Genetic Variation
• Haplotypes
• Humans
• Malaria, Falciparum (blood, drug therapy, epidemiology, parasitology)
• Plasmodium falciparum (drug effects, isolation & purification)
• Point Mutation
• Polymerase Chain Reaction