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Coronary vasospasm leading to an acute myocardial infarction after the administration of dolasetron.

Abstract
The 5-hydroxytryptamine antagonists are commonly used agents for the treatment of postoperative nausea and vomiting. However, these drugs can have significant cardiovascular adverse effects. We report a case of acute myocardial infarction after administration of dolasetron in a 17-year-old adolescent girl during strabismus corrective surgery.
AuthorsAdebola Arole, Henry R Kroll, Morris Brown
JournalJournal of clinical anesthesia (J Clin Anesth) Vol. 17 Issue 1 Pg. 72-4 (Feb 2005) ISSN: 0952-8180 [Print] United States
PMID15721735 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antiemetics
  • Indoles
  • Quinolizines
  • Serotonin Antagonists
  • dolasetron
Topics
  • Acute Disease
  • Adolescent
  • Antiemetics (adverse effects)
  • Coronary Vasospasm (chemically induced, complications, therapy)
  • Electrocardiography
  • Female
  • Humans
  • Indoles (adverse effects)
  • Monitoring, Intraoperative
  • Myocardial Infarction (etiology, therapy)
  • Ophthalmologic Surgical Procedures
  • Quinolizines (adverse effects)
  • Serotonin Antagonists (adverse effects)
  • Strabismus (surgery)

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