Abstract | OBJECTIVE: METHODS: RESULTS: An overall response rate (RR) of 33% was observed in chemotherapy arm with 24 patients showing a partial response (PR) and none showing a complete response (CR). In combination arm the overall RR was 37% with 24 patients showing PR and two showing CR. The median survival times in chemotherapy arm and combination arm were nine and 11 months respectively. The overall survival (OS) rates in chemotherapy arm and combination arm at one year were 32.9% and 39.1%, and at two years, 11.1% and 15.6% respectively. None of these differences were statistically significant (p = 0.20). Toxicity profiles were similar in both arms. CONCLUSIONS:
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Authors | Ashutosh K Pathak, Manisha Bhutani, Randeep Guleria, Sabyasachi Bal, Anant Mohan, Bidhu K Mohanti, Atul Sharma, Raminder Pathak, Narendra K Bhardwaj, Kedar N Prasad, Vinod Kochupillai |
Journal | Journal of the American College of Nutrition
(J Am Coll Nutr)
Vol. 24
Issue 1
Pg. 16-21
(Feb 2005)
ISSN: 0731-5724 [Print] United States |
PMID | 15670980
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antineoplastic Agents
- Antioxidants
- beta Carotene
- Vitamin E
- Ascorbic Acid
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Topics |
- Adult
- Aged
- Antineoplastic Agents
(administration & dosage, adverse effects, therapeutic use)
- Antineoplastic Combined Chemotherapy Protocols
- Antioxidants
(administration & dosage, therapeutic use)
- Ascorbic Acid
(administration & dosage, therapeutic use)
- Carcinoma, Non-Small-Cell Lung
(drug therapy, mortality)
- Drug Synergism
- Female
- Humans
- Lung Neoplasms
(drug therapy, mortality)
- Male
- Middle Aged
- Survival Analysis
- Vitamin E
(administration & dosage, therapeutic use)
- beta Carotene
(administration & dosage, therapeutic use)
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