Abstract |
A follow-up study of 40 patients ( migraine 39, cluster headache 1) previously treated for ergotamine abuse was conducted. Their statements regarding ergotamine intake were checked using butalbital (contained in the suppositories abused by 90% of the patients) as a tracer, and later by contact with the family doctor. Eleven patients abused ergotamine again during a median observation time of 21 months. Nineteen patients had more than a 50% reduction in headache days after withdrawal and half of the patients were relieved of other symptoms of ergotamine toxicity. Even with a failure rate of approximately 25% it is concluded that efforts to withdraw after abuse of ergotamine are worthwhile.
|
Authors | P Tfelt-Hansen, A Krabbe |
Journal | Cephalalgia : an international journal of headache
(Cephalalgia)
Vol. 1
Issue 1
Pg. 29-32
(Mar 1981)
ISSN: 0333-1024 [Print] England |
PMID | 15645831
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Adult
- Aged
- Cluster Headache
(blood, drug therapy, psychology)
- Ergotamine
(therapeutic use)
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Migraine Disorders
(blood, drug therapy, psychology)
- Secondary Prevention
- Substance Withdrawal Syndrome
(blood, psychology)
- Substance-Related Disorders
(blood, prevention & control, psychology)
|