Abstract |
Functional magnetic resonance imaging (fMRI) can detect lateral geniculate nucleus (LGN) activation. We studied LGN function in 5 patients with retrogeniculate homonymous hemianopia using fMRI at 4.0 Tesla during binocular visual stimulation. Decreased activation of visual cortex and LGN on the side of the lesion was observed in all 5 patients. These findings suggest that retrogeniculate lesions are associated with decreased activation of the LGN, due to retrograde degeneration or a functional decrease caused by decreased feedback from ipsilateral visual cortex.
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Authors | Atsushi Miki, Grant T Liu, Edward J Modestino, Gabrielle R Bonhomme, Chia-Shang J Liu, John C Haselgrove |
Journal | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
(Ophthalmologica)
2005 Jan-Feb
Vol. 219
Issue 1
Pg. 11-5
ISSN: 0030-3755 [Print] Switzerland |
PMID | 15627821
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright (c) 2005 S. Karger AG, Basel. |
Topics |
- Adolescent
- Adult
- Female
- Geniculate Bodies
(physiopathology)
- Hemianopsia
(diagnosis, physiopathology)
- Humans
- Magnetic Resonance Imaging
(methods)
- Male
- Middle Aged
- Vision, Binocular
(physiology)
- Visual Cortex
(physiopathology)
- Visual Pathways
(physiopathology)
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