Abstract | BACKGROUND/AIMS: METHODS: Between 1992 and 2003, a total of 60 patients with fulminant hepatic failure were divided into the survival group and the non-survival group, and these groups were compared according to gender, age, etiology, values of the laboratory tests, grade of the encephalopathy that was obtained at the time of admission and the worst clinical status ( hepatic encephalopathy). RESULTS: The mean age of the total patients was 40.9 years (M:F=31:29) and the survival rate was 28.3% (n=17). Drugs (n=25, 12 herbal medicines) and viral infection (n=24, 18 HBV infection) were most common causes. On univariate analysis, the WBC, AST, ALT, total bilirubin and HE IV stage at the time of admission were the significant factors for a poor prognosis. Total bilirubin, albumin and HE IV stage also remained as significant factors at the time of the worst clinical status. On multivariate analysis, total bilirubin (P=0.033) and ALT (P=0.042) at admission were the prognostic factors, and the progression to HE IV stage (P=0.019) or hypoalbuminemia (P=0.028) during hospitalization represented the significant factors for a poor prognosis. CONCLUSIONS:
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Authors | Sung Jae Shin, Sang Hoon Ahn, Hee Man Kim, Ja Kyung Kim, Byung Chang Kim, Jae Hyun Lee, Yong Han Paik, Kwan Sik Lee, Kwang Hyub Han, Chae Yoon Chon, Young Myoung Moon |
Journal | The Korean journal of hepatology
(Korean J Hepatol)
Vol. 10
Issue 4
Pg. 298-307
(Dec 2004)
ISSN: 1738-222X [Print] Korea (South) |
PMID | 15613805
(Publication Type: English Abstract, Journal Article)
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Topics |
- Adult
- Female
- Humans
- Liver Failure, Acute
(diagnosis, etiology, surgery)
- Liver Transplantation
- Male
- Middle Aged
- Prognosis
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