Frequency of haemoglobinopathies and glucose-6-phosphate dehydrogenase deficiency in Basra.

Abstract

Basra, southern Iraq, was mapped for haemoglobinopathies and glucose-6-phosphate dehydrogenase (G6PD) deficiency. Of 1064 couples aged 14-60 years recruited from the Public Health Laboratory, 49 had beta-thalassaemia trait, 69 had sickle-cell trait, 2 had haemoglobin D trait, 2 had haemoglobin C trait and 1 had high persistent fetal haemoglobin. Carriers of major beta-globin disorders comprised 11.48%. G6PD deficiency was detected in 133 individuals (12.5%). Only 10 couples (0.94%) were at risk of having children affected with either sickle-cell disease or beta-thalassaemia major. These defects constitute a real health problem and necessitate a management plan and public health education for early diagnosis and therapy.

• Authors: M K Hassan, J Y Taha, L M Al-Naama, N M Widad, S N Jasim
• Journal: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit (East Mediterr Health J) 2003 Jan-Mar Vol. 9 Issue 1-2 Pg. 45-54 ISSN: 1020-3397 [Print] Egypt
• PMID: 15562732 (Publication Type: Journal Article)

Chemical References

• Hemoglobins, Abnormal
• hemoglobin D
• Fetal Hemoglobin

Topics

• Adolescent
• Adult
• Female
• Fetal Hemoglobin (genetics)
• Gene Frequency (genetics)
• Genetic Carrier Screening
• Genetic Counseling
• Genetic Testing
• Glucosephosphate Dehydrogenase Deficiency (epidemiology, genetics, prevention & control)
• Health Education
• Hemoglobin C Disease (epidemiology, genetics)
• Hemoglobinopathies (epidemiology, genetics, prevention & control)
• Hemoglobins, Abnormal (genetics)
• Humans
• Iraq (epidemiology)
• Male
• Middle Aged
• Molecular Epidemiology
• Needs Assessment
• Population Surveillance
• Prevalence
• Residence Characteristics (statistics & numerical data)
• Risk Factors
• Sickle Cell Trait (epidemiology, genetics)
• beta-Thalassemia (epidemiology)