Candida parapsilosis keratitis following treatment of epithelial ingrowth after laser in situ keratomileusis.

Abstract

PURPOSE:

To present a case of Candida parapsilosis following laser in situ keratomileusis (LASIK).

METHODS:

Retrospective chart review.

RESULTS:

A case report of a 51-year-old woman who underwent bilateral LASIK is presented. Two weeks after the procedure, the patient presented with epithelial ingrowth OD. The ingrowth was treated with flap lifting and scraping, followed by postoperative antibiotics. Four weeks later, the patient presented with numerous interface infiltrates. Smears were positive for yeast forms and cultures grew Candida parapsilosis. Administration of topical and systemic antifungal therapy resulted in clearing of the infection with partial visual recovery.

CONCLUSIONS:

To our knowledge, this represents the first reported case of a post-LASIK Candida parapsilosis keratitis. A high degree of suspicion coupled with rapid and appropriate treatment can result in visual recovery.

• Authors: Renée Solomon, Seth A Biser, Eric D Donnenfeld, Henry D Perry, Sima J Doshi, Chris C Lee
• Journal: Eye & contact lens (Eye Contact Lens) Vol. 30 Issue 2 Pg. 85-6 (Apr 2004) ISSN: 1542-2321 [Print] United States
• PMID: 15260354 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antifungal Agents
• Amphotericin B
• Fluconazole
• Ofloxacin

Topics

• Amphotericin B (therapeutic use)
• Antifungal Agents (therapeutic use)
• Candidiasis (diagnosis, drug therapy, microbiology)
• Debridement
• Drug Therapy, Combination
• Epithelium, Corneal (pathology)
• Eye Infections, Fungal (diagnosis, drug therapy, microbiology)
• Female
• Fluconazole (therapeutic use)
• Humans
• Keratitis (diagnosis, drug therapy, microbiology)
• Keratomileusis, Laser In Situ (adverse effects)
• Middle Aged
• Ofloxacin (therapeutic use)
• Postoperative Complications
• Retrospective Studies
• Surgical Flaps (pathology)