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Epidemiological investigation of bloodstream infections by extended spectrum cephalosporin-resistant Escherichia coli in a Taiwanese teaching hospital.

Abstract
In an epidemiologic and case-control study including 30 case patients over a 3.5-year period in a Taiwanese university hospital, only beta-lactamase inhibitor use and extended-spectrum cephalosporin use were identified as independent risk factors for nosocomial CMY-2-producing Escherichia coli bloodstream infection, and CMY-2 producers were found more prevalent than extended-spectrum beta-lactamase-producing isolates.
AuthorsJing-Jou Yan, Wen-Chien Ko, Jiunn-Jong Wu, Shu-Huei Tsai, Chin-Luan Chuang
JournalJournal of clinical microbiology (J Clin Microbiol) Vol. 42 Issue 7 Pg. 3329-32 (Jul 2004) ISSN: 0095-1137 [Print] United States
PMID15243108 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • beta-lactamase CMY-2
  • beta-Lactamases
Topics
  • Adult
  • Aged
  • Bacteremia (epidemiology, etiology)
  • Case-Control Studies
  • Cephalosporin Resistance
  • Escherichia coli (drug effects, enzymology)
  • Escherichia coli Infections (epidemiology, etiology)
  • Female
  • Hospitals, Teaching
  • Humans
  • Male
  • Middle Aged
  • Random Amplified Polymorphic DNA Technique
  • Risk Factors
  • Taiwan (epidemiology)
  • beta-Lactamases (biosynthesis)

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