Abstract | OBJECTIVE: METHODS: RESULTS: All of the four drugs significantly prolonged survival over controls. With both isolates, kidney counts were reduced significantly below controls for amphotericin B, fluconazole and posaconazole. However, voriconazole was less effective than the other antifungals. CONCLUSION:
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Authors | Steve Hernandez, Gloria M Gonzalez, Dora I McCarthy, Arnaldo Lopes Colombo, Laura K Najvar, Rosie Bocanegera, John R Graybill |
Journal | The Journal of antimicrobial chemotherapy
(J Antimicrob Chemother)
Vol. 54
Issue 2
Pg. 477-80
(Aug 2004)
ISSN: 0305-7453 [Print] England |
PMID | 15215225
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Antifungal Agents
- Pyrimidines
- Triazoles
- posaconazole
- Amphotericin B
- Fluconazole
- Voriconazole
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Topics |
- Amphotericin B
(therapeutic use)
- Animals
- Antifungal Agents
(therapeutic use)
- Candidiasis
(drug therapy, microbiology)
- Colony Count, Microbial
- Fluconazole
(therapeutic use)
- Kidney
(microbiology)
- Male
- Mice
- Mice, Inbred ICR
- Microbial Sensitivity Tests
- Neutropenia
(microbiology)
- Organ Size
- Pyrimidines
(therapeutic use)
- Spleen
(microbiology)
- Survival Analysis
- Triazoles
(therapeutic use)
- Voriconazole
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