[The European prospective investigation about cancer and nutrition (EPIC)].

Abstract

EPIC is a prospective multi-center study coordinated by the International Agency for Research on Cancer (IARC) operating under the WHO which commenced in 1993 with the collecting of data and blood samples at twenty-three centers in ten European countries (Germany, Denmark, Spain, France, Greece, the Netherlands, Italy, Norway, the United Kingdom and Sweden). In Spain, this study was conducted in five geographic areas (Asturias, Granada, Guipuzcoa, Murcia and Navarre). This study included a total of 519,978 individuals (366,521 of whom were females), blood samples for laboratory analysis being available for a total of 385,719 of these individuals. To date, a total of 24,195 incident cancer cases have been identified. The results of the food intake comparison among the twenty-three European centers were published in 2002, in a European Nutrition journal supplement. The initial EPIC results concerning the relationship between diet and cancer show the intake of fiber, fruits and vegetables to have an effect on protect against colon and rectal cancer, the intake of fruits to have an effect on protect against lung cancer and the intake of fruits and vegetables on the upper digestive tract, whilst a high intake of fruits and vegetables has been shown to have no effect on prostate cancer. Using a seven-day diary for evaluating saturated fat intake, a high intake of saturated fats has been shown to increase the risk of breast cancer.

• Authors: Carlos A González, Carmen Navarro, Carmen Martínez, José R Quirós, Miren Dorronsoro, Aurelio Barricarte, María José Tormo, Antonio Agudo, María Dolores Chirlaque, Pilar Amiano, Eva Ardanaz, Guillem Pera, María José Sánchez, Antonio Berenguer
• Journal: Revista espanola de salud publica (Rev Esp Salud Publica) 2004 Mar-Apr Vol. 78 Issue 2 Pg. 167-76 ISSN: 1135-5727 [Print] Spain
• Vernacular Title: El Estudio Prospectivo Europeo Sobre Cáncer y Nutrición (EPIC).
• PMID: 15199795 (Publication Type: Comparative Study, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)

Chemical References

• Dietary Fats
• Dietary Fiber

Topics

• Adult
• Aged
• Dietary Fats (adverse effects)
• Dietary Fiber
• Europe
• Feeding Behavior
• Female
• Fruit
• Humans
• Male
• Middle Aged
• Neoplasms (epidemiology, prevention & control)
• Nutritional Physiological Phenomena
• Prospective Studies
• Risk Factors
• Vegetables