Abstract | BACKGROUND: RESULTS: We used a multivariate structural equation model (SEM) approach to scan the genome for loci involved in the metabolic syndrome. We found moderate evidence for linkage on chromosomes 2, 3, 11, 13, and 15, and these loci appear to have different relative effects on the component traits of the metabolic syndrome. CONCLUSION:
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Authors | Catherine M Stein, Yeunjoo Song, Robert C Elston, Gyungah Jun, Hemant K Tiwari, Sudha K Iyengar |
Journal | BMC genetics
(BMC Genet)
Vol. 4 Suppl 1
Pg. S99
(Dec 31 2003)
ISSN: 1471-2156 [Electronic] England |
PMID | 14975167
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
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Topics |
- Chromosomes, Human, Pair 11
(genetics)
- Chromosomes, Human, Pair 13
(genetics)
- Chromosomes, Human, Pair 15
(genetics)
- Chromosomes, Human, Pair 2
(genetics)
- Chromosomes, Human, Pair 3
(genetics)
- Factor Analysis, Statistical
- Female
- Genes
(physiology)
- Genetic Markers
(genetics)
- Genetic Testing
(statistics & numerical data)
- Genome, Human
- Humans
- Male
- Metabolic Syndrome
(epidemiology, genetics)
- Middle Aged
- Models, Genetic
- Multivariate Analysis
- Quantitative Trait Loci
(genetics)
- Quantitative Trait, Heritable
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