Pityriasis lichenoides--an immune complex disease.

Abstract

Circulating immune complexes have been detected in patients with pityriasis lichenoides during disease activity when IgM and C3 have been observed in dermal vessels on direct immunofluorescence of fresh lesions. This implies that pityriasis lichenoides is an immune complex disorder and that deposited complexes play a part in the pathogenesis of the condition. There is a characteristic pattern of immunofluorescence which may be a diagnostic aid.

• Authors: R Clayton, G Haffenden, A Du Vivier, J Burton, J Mowbray
• Journal: The British journal of dermatology (Br J Dermatol) Vol. 97 Issue 6 Pg. 629-34 (Dec 1977) ISSN: 0007-0963 [Print] England
• PMID: 146510 (Publication Type: Journal Article)

Chemical References

• Antigen-Antibody Complex
• Complement C3
• Immunoglobulin M

Topics

• Adolescent
• Adult
• Aged
• Antigen-Antibody Complex
• Child
• Complement C3 (analysis)
• Female
• Fluorescent Antibody Technique
• Humans
• Immune Complex Diseases
• Immunoglobulin M (analysis)
• Male
• Middle Aged
• Pityriasis (immunology)