Intranasal anticholinergic therapy of rhinorrhea.

Abstract

This article reviews the role of anticholinergic therapy for the rhinorrhea that occurs in various rhinopathies, including irritant reactions, perennial nonallergic rhinitis, viral infection rhinitis, allergic rhinitis, and temperature-induced rhinitis. The use of a topical anticholinergic medication, ipratropium bromide, and its ability to inhibit methacholine and rhinitis-induced hypersecretion is emphasized. Ipratropium bromide appears to be both safe and effective in reducing this troublesome symptom.

• Authors: E O Meltzer
• Journal: The Journal of allergy and clinical immunology (J Allergy Clin Immunol) Vol. 90 Issue 6 Pt 2 Pg. 1055-64 (Dec 1992) ISSN: 0091-6749 [Print] United States
• PMID: 1460208 (Publication Type: Journal Article, Review)

Chemical References

• Parasympatholytics
• Ipratropium

Topics

• Administration, Intranasal
• Humans
• Ipratropium (administration & dosage, adverse effects)
• Nasal Mucosa (drug effects, metabolism)
• Parasympatholytics (administration & dosage)
• Rhinitis (drug therapy)
• Rhinitis, Allergic, Perennial (drug therapy)
• Rhinitis, Allergic, Seasonal (drug therapy)
• Virus Diseases (drug therapy)