[Effects of dicetel on gastrointestinal motility and vegetative dysfunction in patients with duodenal ulcer].

Abstract

The great majority of patients with duodenal ulcer (DU) given a single oral dose (50 mg) of dicetel (pinaverium bromide)--a selective blocker of calcium channels--showed optimization of vegetative reactivity and vegetative support of physical and mental activities. This contributes to relief of psychovegetative syndrome of the modulation of dysfunctions of proximal gastrointestinal tract (GIT). The addition of dicetel to combined treatment of PH shortened healing of DU, relieved pain, stopped gastric and intestinal dyspepsia, corrected motor-tonic defects of the proximal GIT caused by dysfunction of different links of the regulatory-adaptive system.

• Authors: E S Golovanova, T Iu Kravtsova, O L Vysokova
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 81 Issue 8 Pg. 31-5 ( 2003) ISSN: 0023-2149 [Print] Russia (Federation)
• Vernacular Title: Vliianie ditsetela na motoriku zheludochno-kishechnogo trakta i vegetativnuiu disfunktsiiu u bol'nykh iazvennoĭ bolezn'iu dvenadtstiperstnoĭ kishki.
• PMID: 14520942 (Publication Type: English Abstract, Journal Article)

Chemical References

• Calcium Channel Blockers
• Morpholines
• pinaverium

Topics

• Adolescent
• Adult
• Calcium Channel Blockers (pharmacology)
• Duodenal Ulcer (drug therapy, physiopathology)
• Enteric Nervous System (drug effects, physiopathology)
• Gastrointestinal Motility (drug effects)
• Humans
• Male
• Middle Aged
• Morpholines (pharmacology)