Long-term use of gamma-linolenic acid-enriched fat emulsion (PFE 4501): case report.

Abstract

A new gamma-linolenic acid-enriched fat emulsion (PFE 4501) was given for 13 mo as part of a home parenteral nutrition regimen to a 28-yr-old patient with cystic fibrosis. Blood biochemistry, hematological data, and fatty acid profile were followed. No side effects were reported, and pulmonary function tests remained stable. gamma-Linolenic acid appears to be safe for clinical use and may benefit patients with derangements in essential fatty acid metabolism. The potential role of a gamma-linolenic acid-enriched intravenous fat emulsion is discussed.

• Authors: E Söreide, B Skeie, D P Katz, T Manner, J Askanazi
• Journal: Nutrition (Burbank, Los Angeles County, Calif.) (Nutrition) 1992 May-Jun Vol. 8 Issue 3 Pg. 182-5 ISSN: 0899-9007 [Print] United States
• PMID: 1326350 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Drug Combinations
• Fat Emulsions, Intravenous
• Linolenic Acids
• Phospholipids
• pediatric fat emulsion 4501
• gamma-Linolenic Acid
• Soybean Oil
• Glycerol

Topics

• Adult
• Cystic Fibrosis (therapy)
• Drug Combinations
• Fat Emulsions, Intravenous
• Female
• Glycerol (therapeutic use)
• Humans
• Linolenic Acids (administration & dosage, therapeutic use)
• Parenteral Nutrition
• Parenteral Nutrition, Home
• Phospholipids (therapeutic use)
• Soybean Oil (therapeutic use)
• gamma-Linolenic Acid