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Urinary beta 2-microglobulin in premature infants with chorioamnionitis and chronic lung disease.

Abstract
The urinary beta(2)-microglobulin (MG) concentration on day 0 to 2 was significantly higher in premature infants with chorioamnionitis (CAM) than in infants without CAM and in infants who developed chronic lung disease (CLD) than in those who did not. We propose that an elevated urinary beta(2)-MG can indicate a fetal inflammatory response and identify neonates at risk for the development of CLD.
AuthorsShigeru Nishimaki, Yoshio Shima, Miho Sato, Hiromi An, Michiru Hashimoto, Yoshiko Nishiyama, Shiho Iwasaki, Itaru Tateishi, Kazuo Seki, Shumpei Yokota
JournalThe Journal of pediatrics (J Pediatr) Vol. 143 Issue 1 Pg. 120-2 (Jul 2003) ISSN: 0022-3476 [Print] United States
PMID12915837 (Publication Type: Journal Article)
Chemical References
  • beta 2-Microglobulin
Topics
  • Chorioamnionitis (complications, urine)
  • Chronic Disease
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Kidney Function Tests
  • Lung Diseases (complications, urine)
  • Male
  • Mothers
  • Pregnancy
  • Pregnancy Complications
  • Respiration, Artificial
  • beta 2-Microglobulin (urine)

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