Abstract | BACKGROUND: METHODS: RESULTS: CONCLUSIONS:
Desipramine may be a useful adjunctive medication in facilitating opioid and cocaine abstinence in opioid-maintained patients. The efficacy of opioid medications to treat opioid or cocaine dependence may differ by sex. These findings highlight the importance of including sex as a factor when examining treatment outcome in these types of trials.
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Authors | A H Oliveto, A Feingold, R Schottenfeld, P Jatlow, T R Kosten |
Journal | Archives of general psychiatry
(Arch Gen Psychiatry)
Vol. 56
Issue 9
Pg. 812-20
(Sep 1999)
ISSN: 0003-990X [Print] United States |
PMID | 12884887
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Analgesics, Opioid
- Antidepressive Agents, Tricyclic
- Narcotic Antagonists
- Buprenorphine
- Desipramine
- Methadone
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Topics |
- Adult
- Analgesics, Opioid
(therapeutic use)
- Antidepressive Agents, Tricyclic
(therapeutic use)
- Buprenorphine
(therapeutic use)
- Cocaine-Related Disorders
(drug therapy, epidemiology)
- Comorbidity
- Desipramine
(therapeutic use)
- Drug Administration Schedule
- Drug Therapy, Combination
- Female
- Heroin Dependence
(epidemiology, rehabilitation)
- Humans
- Male
- Methadone
(therapeutic use)
- Middle Aged
- Narcotic Antagonists
(therapeutic use)
- Opioid-Related Disorders
(epidemiology, rehabilitation)
- Sex Factors
- Treatment Outcome
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