Element of caution: a case of reversible cytopenias associated with excessive zinc supplementation.

Abstract

Zinc is a common supplement and is widely available as a standard component of many over-the-counter products. A number of reports have identified an association between excessive zinc intake and severe cytopenia. We report a case of zinc-induced copper deficiency in a young adult to illustrate this under-recognized cause of anemia and neutropenia.

• Authors: Julie A Irving, Andre Mattman, Gillian Lockitch, Kevin Farrell, Louis D Wadsworth
• Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne (CMAJ) Vol. 169 Issue 2 Pg. 129-31 (Jul 22 2003) ISSN: 0820-3946 [Print] Canada
• PMID: 12874162 (Publication Type: Case Reports, Journal Article)

Chemical References

• Nonprescription Drugs
• Zinc

Topics

• Adult
• Anemia, Sideroblastic (chemically induced)
• Dietary Supplements (adverse effects)
• Female
• Humans
• Neutropenia (chemically induced)
• Nonprescription Drugs
• Pantothenate Kinase-Associated Neurodegeneration (drug therapy)
• Zinc (adverse effects)