Choroidal neovascular membrane associated with optic nerve coloboma in a patient with CHARGE association.

Abstract

PURPOSE:

To report a patient with CHARGE association (coloboma, heart disease, choanal atresia, growth retardation, genital hypoplasia, and ear abnormalities) who developed a choroidal neovascular membrane in association with an optic nerve coloboma.

DESIGN:

Interventional/observational case report.

METHOD:

A 21-month-old boy with CHARGE association developed a grayish choroidal neovascular membrane associated with lipid exudation, subretinal fluid, and retinal hemorrhage at the temporal edge of his right optic nerve coloboma.

RESULTS:

The patient underwent transpupillary diode laser of the choroidal neovascular membrane. Five months later, it and the serous retinal detachment had resolved.

CONCLUSIONS:

Patients with CHARGE association may develop choroidal neovascular membrane with serous retinal detachments in association with optic nerve colobomas. These neovascular membranes may be treated successfully with transpupillary diode laser.

• Authors: Medhat F Guirgis, Gregg T Lueder
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 135 Issue 6 Pg. 919-20 (Jun 2003) ISSN: 0002-9394 [Print] United States
• PMID: 12788148 (Publication Type: Case Reports, Journal Article)

Topics

• Abnormalities, Multiple
• Choanal Atresia (complications)
• Choroidal Neovascularization (complications, surgery)
• Coloboma (complications)
• Ear (abnormalities)
• Genitalia, Male (abnormalities)
• Growth Disorders (complications)
• Heart Defects, Congenital (complications)
• Humans
• Infant, Newborn
• Laser Coagulation
• Male
• Optic Nerve (abnormalities)
• Syndrome