Airborne allergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate at a paint factory.

Abstract

3-Iodo-2-propynyl-butylcarbamate (IPBC) is a fungicide used in both industrial products and cosmetics. We report the first case of allergic contact dermatitis from airborne exposure to this preservative. A 34-year-old female production worker at a paint factory developed dermatitis on air-exposed skin areas. Patch testing showed a ++ reaction to the preservative IPBC 0.01% in petrolatum. The compound was used as a preservative in wood treatment products manufactured at her work place. Based on animal studies, IPBC is considered safe as a cosmetic preservative. However, widespread use of the chemical might lead to increasing levels of contact allergy, and therefore, close monitoring of IPBC is recommended.

• Authors: Charlotte Devantier Jensen, Jens Thormann, Klaus Ejner Andersen
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 48 Issue 3 Pg. 155-7 (Mar 2003) ISSN: 0105-1873 [Print] England
• PMID: 12755730 (Publication Type: Case Reports, Journal Article)

Chemical References

• Allergens
• Carbamates
• Preservatives, Pharmaceutical
• 3-iodo-2-propynylbutylcarbamate

Topics

• Adult
• Air Pollution, Indoor (adverse effects)
• Allergens (adverse effects)
• Carbamates (adverse effects)
• Dermatitis, Allergic Contact (diagnosis, etiology)
• Dermatitis, Occupational (diagnosis, etiology)
• Diagnosis, Differential
• Female
• Humans
• Paint (adverse effects)
• Patch Tests
• Preservatives, Pharmaceutical (adverse effects)