Two cases of cerebral aspergillosis successfully treated with voriconazole.

Abstract

Described here are two cases of cerebral aspergillosis successfully treated with voriconazole after the failure of first-line treatment with amphotericin B deoxycholate. In both cases, clinical and radiological cure was achieved within 6 weeks. Voriconazole should be considered as first-line therapy for cerebral aspergillosis.

• Authors: V de Lastours, A Lefort, M Zappa, V Dufour, N Belmatoug, B Fantin
• Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (Eur J Clin Microbiol Infect Dis) Vol. 22 Issue 5 Pg. 297-9 (May 2003) ISSN: 0934-9723 [Print] Germany
• PMID: 12740666 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antifungal Agents
• Pyrimidines
• Triazoles
• Voriconazole

Topics

• Administration, Oral
• Antifungal Agents (administration & dosage)
• Brain Diseases (diagnosis, drug therapy)
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Female
• Follow-Up Studies
• Humans
• Infusions, Intravenous
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Neuroaspergillosis (diagnosis, drug therapy)
• Pyrimidines (administration & dosage)
• Treatment Outcome
• Triazoles (administration & dosage)
• Voriconazole