Abstract | BACKGROUND: METHODS: One hundred eighty patients scheduled for elective coronary artery bypass grafting were randomly divided into two groups: propofol group (n = 90) and fentanyl group (n = 90). After induction of anesthesia, a fiberoptic oximetry oxygen saturation catheter was inserted into the right jugular bulb to monitor jugular venous oxygen hemoglobin saturation continuously. Hemodynamic measurements and arterial and jugular venous blood gases were measured at seven time points. All patients underwent a battery of neurologic and neuropsychological tests on the day before the operation and at 6 months after the operation. RESULTS: CONCLUSIONS:
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Authors | Yuji Kadoi, Shigeru Saito, Fumio Kunimoto, Fumio Goto, Nao Fujita |
Journal | The Annals of thoracic surgery
(Ann Thorac Surg)
Vol. 75
Issue 3
Pg. 840-6
(Mar 2003)
ISSN: 0003-4975 [Print] Netherlands |
PMID | 12645704
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Oxyhemoglobins
- Fentanyl
- Propofol
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Topics |
- Aged
- Anesthesia, General
- Anesthesia, Intravenous
- Blood Gas Analysis
- Brain
(blood supply)
- Cardiopulmonary Bypass
- Cognition Disorders
(chemically induced, diagnosis)
- Coronary Artery Bypass
- Female
- Fentanyl
- Humans
- Male
- Middle Aged
- Neurologic Examination
- Neuropsychological Tests
- Oxygen Consumption
(drug effects)
- Oxyhemoglobins
(metabolism)
- Postoperative Complications
(chemically induced, diagnosis)
- Propofol
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