Abstract | BACKGROUND: METHODS: We retrospectively analyzed the incidence rate of side effects associated with 250 mg of ferric gluconate infused over 1 to 4 hrs. Seventy-nine treatments were administered to 40 patients who had severe CRF. Five patients had received treatments on consecutive days (2 to 4 treatments). RESULTS: Four treatments in two patients were associated with side effects, which included diarrhea, vomiting, low back pain, hypotension and burning sensation in feet. The duration of infusion did not influence the side effect profile. CONCLUSION: Our preliminary results suggest that 250 mg of ferric gluconate infused over 14 hrs may be safe with infrequent side effects (5%). It is also more convenient and practical for patients who are not on maintenance HD.
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Authors | Anil K Jain, Bahar Bastani |
Journal | Journal of nephrology
(J Nephrol)
2002 Nov-Dec
Vol. 15
Issue 6
Pg. 681-3
ISSN: 1121-8428 [Print] Italy |
PMID | 12495284
(Publication Type: Journal Article)
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Chemical References |
- Ferric Compounds
- ferric gluconate
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Topics |
- Adult
- Aged
- Anemia, Iron-Deficiency
(drug therapy, etiology)
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Female
- Ferric Compounds
(administration & dosage, adverse effects)
- Follow-Up Studies
- Humans
- Infusions, Intravenous
- Kidney Failure, Chronic
(diagnosis, drug therapy, therapy)
- Male
- Maximum Tolerated Dose
- Middle Aged
- Renal Dialysis
(adverse effects, methods)
- Retrospective Studies
- Risk Assessment
- Treatment Outcome
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