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Cellular mechanisms of cyclophosphamide resistance: model studies in human medulloblastoma cell lines.

AuthorsHenry S Friedman, Stewart P Johnson, O Michael Colvin
JournalCancer treatment and research (Cancer Treat Res) Vol. 112 Pg. 199-209 ( 2002) ISSN: 0927-3042 [Print] United States
PMID12481718 (Publication Type: Journal Article, Review)
Chemical References
  • Antineoplastic Agents, Alkylating
  • Cyclophosphamide
  • DNA
  • Aldehyde Dehydrogenase
  • Glutathione Transferase
  • Glutathione
  • perfosfamide
Topics
  • Aldehyde Dehydrogenase (metabolism)
  • Antineoplastic Agents, Alkylating (therapeutic use)
  • Central Nervous System Neoplasms (drug therapy)
  • Cyclophosphamide (analogs & derivatives, pharmacology, therapeutic use)
  • DNA (metabolism)
  • DNA Repair
  • Drug Resistance, Neoplasm
  • Glutathione (metabolism)
  • Glutathione Transferase (metabolism)
  • Humans
  • Medulloblastoma (drug therapy)
  • Models, Chemical
  • Tumor Cells, Cultured

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