Improvement of acquired pendular nystagmus by gabapentin: case report.

Abstract

Acquired Pendular Nystagmus (APN) may cause distressing visual symptoms in patients who are already suffering a severe general disease. Averbuch-Heller et al. conducted the first double-blind controlled study on treatment for APN. They showed that gabapentin substantially reduces pendular nystagmus and significantly increases visual acuity in the majority of patients. We present a patient with APN due to multiple sclerosis who suffered severe oscillopsy and reduction of visual acuity and who substantially benefited from a trial treatment with this agent.

• Authors: K Fabre, H Smet-Dieleman, T Zeyen
• Journal: Bulletin de la Societe belge d'ophtalmologie (Bull Soc Belge Ophtalmol) Issue 282 Pg. 43-6 ( 2001) ISSN: 0081-0746 [Print] Belgium
• PMID: 12455139 (Publication Type: Case Reports, Journal Article)

Chemical References

• Acetates
• Amines
• Cyclohexanecarboxylic Acids
• gamma-Aminobutyric Acid
• Gabapentin
• Baclofen

Topics

• Acetates (therapeutic use)
• Administration, Oral
• Amines
• Baclofen (administration & dosage)
• Cyclohexanecarboxylic Acids
• Female
• Gabapentin
• Humans
• Middle Aged
• Multiple Sclerosis (complications)
• Nystagmus, Pathologic (drug therapy, etiology)
• Treatment Outcome
• gamma-Aminobutyric Acid