Corneal opacifications in a low high density lipoprotein syndrome: suspicion of fish eye disease: a case report.

Abstract

A 49 year old patient with progressive massive bilateral corneal opacifications associated with a HDL (high-density-lipoprotein) deficiency is described. The opacifications started at the age of twenty and progressed slowly. They were found diffusely over the cornea, though more in the corneal periphery. A penetrating keratoplasty at the right eye was performed. The diagnosis of Fish Eye Disease was put forward on the basis of the ophthalmological, clinical, biochemical and pathological appearance. After 2 year follow-up, the graft was clear. The final distance and near vision of the right eye was 8/10 and Snellen 1 respectively.

• Authors: M De Smedt, R Van Ginderdeuren, R De Vos, A Mertens, E Muls, B Foets
• Journal: Bulletin de la Societe belge d'ophtalmologie (Bull Soc Belge Ophtalmol) Issue 282 Pg. 25-30 ( 2001) ISSN: 0081-0746 [Print] Belgium
• PMID: 12455137 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Corneal Opacity (etiology, pathology, surgery)
• Disease Progression
• Female
• Humans
• Keratoplasty, Penetrating
• Middle Aged
• Tangier Disease (complications, diagnosis)