Drug reaction to ursodeoxycholic acid: lichenoid drug eruption in an infant using ursodeoxycholic acid for neonatal hepatitis.

Abstract

Lichenoid drug eruptions are skin reactions associated with a number of drugs and chemicals. They are rare in infants. We report here an infant who presented with neonatal hepatitis and who was being treated with ursodeoxycholic acid. The infant developed lichenoid skin eruptions in the third week of the therapy. The lesions have resolved two months after the discontinuation of the drug. To our knowledge, this is the first infant case of lichenoid drug eruption associated with ursodeoxycholic acid.

• Authors: Benal Büyükgebiz, Nur Arslan, Yeşim Oztürk, Cüneyt Soyal, Banu Lebe
• Journal: Journal of pediatric gastroenterology and nutrition (J Pediatr Gastroenterol Nutr) Vol. 35 Issue 3 Pg. 384-6 (Sep 2002) ISSN: 0277-2116 [Print] United States
• PMID: 12352534 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cholagogues and Choleretics
• Ursodeoxycholic Acid

Topics

• Cholagogues and Choleretics (adverse effects)
• Hepatitis (drug therapy)
• Humans
• Infant
• Lichenoid Eruptions (etiology)
• Male
• Ursodeoxycholic Acid (adverse effects)