Abstract | PURPOSE: The purpose of this study was to determine the optimal concentration and volumes of ropivacaine for dental anesthesia as regards onset and duration of action. SUBJECTS AND METHODS: Thirty healthy individuals with a mean age of 32 years participated in the study on a voluntary basis. All subjects received a ropivacaine injection in 1 of 3 randomized concentrations (2.0, 5.0, or 7.5 mg/mL) for infiltration anesthesia and mandibular nerve block in a double-blind manner. The onset time and duration of anesthesia were assessed by electric pulp test, pinprick test of the gingiva, and presence of feeling of numbness of the lip. RESULTS: Regardless of dose, only 5 patients received pulpal anesthesia after infiltration, but all 3 concentrations anesthetized the gingiva and upper lip. The onset of pulpal anesthesia occurred less than 5 minutes after injection and lasted for 4 to 58 minutes. Pinprick anesthesia lasted for 8 to 48 minutes, and numbness of the upper lip lasted 1 to 4 hours. The effectiveness of the mandibular nerve block with regard to pulpal anesthesia was dose dependent. Only ropivacaine at 7.5 mg/mL produced sufficient anesthesia. The onset of pulpal anesthesia occurred less than 10 minutes after injection and lasted for 2 to 6 hours. Pinprick anesthesia lasted for 3 to 6 hours and numbness of the lower lip lasted for 5 to 9 hours. CONCLUSION:
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Authors | Malin Ernberg, Sigvard Kopp |
Journal | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
(J Oral Maxillofac Surg)
Vol. 60
Issue 9
Pg. 1004-10; discussion 1010-11
(Sep 2002)
ISSN: 0278-2391 [Print] United States |
PMID | 12215984
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | Copyright 2002 American Association of Oral and Maxillofacial Surgeons |
Chemical References |
- Amides
- Anesthetics, Local
- Ropivacaine
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Topics |
- Adolescent
- Adult
- Amides
(administration & dosage, adverse effects)
- Anesthesia Recovery Period
- Anesthesia, Dental
(methods)
- Anesthesia, Local
(methods)
- Anesthetics, Local
(administration & dosage, adverse effects)
- Dental Pulp Test
- Dose-Response Relationship, Drug
- Double-Blind Method
- Female
- Humans
- Hypesthesia
(chemically induced)
- Male
- Mandibular Nerve
- Nerve Block
(methods)
- Ropivacaine
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