[Treatment of severe viral hepatitis with artificial liver support system].

Abstract

BACKGROUND:

To investigate the method and therapeutic efficacy of artificial liver support system (ALSS) in treatment of severe viral hepatitis.

METHODS:

A total of 83 patients including 66 with severe viral hepatitis were treated with ALSS using Baxter-550 artificial kidney and Biologic-DT system.

RESULTS:

The levels of mean bilirubin, ALT, AST, BUN, Cr and endotoxin was significantly decreased after the treatment. Of the 66 patients?with severe viral hepatitis, 31(47.0%) had improvement in symptoms and 35 (53.0%) died or left hospital. In the control group,50(27.6%) out of the 181 had improvement in symptoms and 131(72.4%) died or left hospital.

CONCLUSIONS:

ALSS could exert certain therapeutic effects on severe viral hepatitis.

• Authors: Baosen Li, Shaojie Xin, Hanqian Xing, Jun Zhao, Zhengsheng Zou, Bin Zhang, Deyong Chen, Yuanli Mao
• Journal: Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology (Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi) Vol. 16 Issue 2 Pg. 157-9 (Jun 2002) ISSN: 1003-9279 [Print] China
• PMID: 12196829 (Publication Type: English Abstract, Journal Article)

Topics

• Adult
• Female
• Hepatitis, Viral, Human (therapy)
• Humans
• Liver, Artificial
• Male
• Middle Aged
• Treatment Outcome