Progesterone receptor expression in angioleiomyoma of the nasal cavity.

Abstract

In recent years sex steroid receptors have been identified in several types of human neoplasia. Angioleiomyoma of the nasal cavity and paranasal sinus is an extremely rare benign neoplasm which is more common in females (3.75:1 female:male ratio). To the best of our knowledge, only approximately 25 cases have been described. We describe a new case of angioleiomyoma of the nasal cavity that was found to be progesterone-receptor positive and oestrogen-receptor negative on immunohistochemical analysis. We suggest that the growth of this tumour may be hormone-dependent.

• Authors: Gino Marioni, Rosario Marchese-Ragona, Severino Fernandez, Juan Bruzon, Filippo Marino, Alberto Staffieri
• Journal: Acta oto-laryngologica (Acta Otolaryngol) Vol. 122 Issue 4 Pg. 408-12 (Jun 2002) ISSN: 0001-6489 [Print] England
• PMID: 12125998 (Publication Type: Case Reports, Journal Article)

Chemical References

• Receptors, Progesterone

Topics

• Aged
• Angiomyoma (metabolism, pathology)
• Diagnosis, Differential
• Endothelium (metabolism, pathology)
• Female
• Humans
• Middle Aged
• Muscle, Smooth (metabolism, pathology)
• Nasal Cavity (metabolism, pathology)
• Paranasal Sinus Neoplasms (metabolism, pathology)
• Receptors, Progesterone (metabolism)