Sideroblastic anemia with splenic abscess and fatal thromboemboli after splenectomy.

Abstract

A man with sideroblastic anemia had a splenectomy because of a salmonella abscess of the spleen that had ruptured into the colon. Two months later he developed recurrent thrombophiebitis and fatal thromboembolism associated with thrombocytosis. A review of the literature showed multiple additional cases of sideroblastic anemia with thrombocytosis and thromboembolism after splenectomy. In many of these cases the patient died. Splenectomy for treatment of a sideroblastic anemia probable is contraindicated. If splenectomy is done, long-term therapy to avoid thromboembolic complications probably should be maintained for many months or even years.

• Authors: S H Aleali, O Castro, R P Spencer, S C Finch
• Journal: Annals of internal medicine (Ann Intern Med) Vol. 83 Issue 5 Pg. 661-3 (Nov 1975) ISSN: 0003-4819 [Print] United States
• PMID: 1200498 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)

Topics

• Abscess (complications, surgery)
• Adult
• Anemia, Sideroblastic (complications)
• Femoral Vein
• Humans
• Male
• Pulmonary Embolism (mortality)
• Salmonella Infections (complications, surgery)
• Splenectomy (adverse effects)
• Splenic Diseases (complications, surgery)
• Thromboembolism (etiology, mortality)
• Thrombosis (mortality)