Abstract |
Microsporum canis is the dermatophyte most commonly responsible for ringworm in cats. The purpose of this paper was to evaluate the in vivo efficacy of oral terbinafine ( Lamisil; Sandoz) in the treatment of feline ringworm caused by M canis, and to consider this drug as an alternative to griseofulvin or imidazoles. Fifteen cats infected with M canis were treated orally once daily with 30 mg/kg of terbinafine over a 2-week period. All treated animals were checked for dermatophytes on the last day of treatment, a month later and 3 months after the last administration of the drug. Only 12 cats could be used in the whole trial and 11 of these (92%) showed a complete cure. Terbinafine could be an effective alternative to griseofulvin when fungal resistance or idiosyncrasic intolerance are shown and, compared with griseofulvin, could give a faster rate of cure and less relapses.
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Authors | F Mancianti, F Pedonese, F Millanta, L Guarnieri |
Journal | Journal of feline medicine and surgery
(J Feline Med Surg)
Vol. 1
Issue 1
Pg. 37-41
(03 1999)
ISSN: 1098-612X [Print] England |
PMID | 11919014
(Publication Type: Evaluation Study, Journal Article)
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Copyright | Copyright 1999 European Society of Feline Medicine. |
Chemical References |
- Antifungal Agents
- Naphthalenes
- Itraconazole
- Griseofulvin
- Terbinafine
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Topics |
- Administration, Oral
- Animals
- Antifungal Agents
(administration & dosage, therapeutic use)
- Cat Diseases
(drug therapy)
- Cats
- Dermatomycoses
(drug therapy, veterinary)
- Female
- Griseofulvin
(therapeutic use)
- Itraconazole
(therapeutic use)
- Male
- Microsporum
- Naphthalenes
(administration & dosage, therapeutic use)
- Terbinafine
- Treatment Outcome
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