Complete response of a stage IV mucinous cystadenocarcinoma of the ovary to systemic chemotherapy employing paclitaxel and carboplatin.

Abstract

BACKGROUND:

The survival rate of patients with advanced-stage mucinous cystadenocarcinoma of the ovary is dismal and no best treatment is known. We report a case of complete response of a stage IV mucinous cystadenocarcinoma of the ovary to systemic chemotherapy employing paclitaxel and carboplatin.

CASE:

A 51-year-old nullipara diagnosed with International Federation of Gynecology and Obstetrics stage IV mucinous cystadenocarcinoma of the ovary underwent cytoreductive surgery followed by systemic chemotherapy employing paclitaxel and carboplatin every 4 weeks for 3 courses. The patient tolerated chemotherapy well, demonstrated a remarkable response showing no evidence of malignancy at a second-look laparotomy. As a consolidation chemotherapy after negative second-look laparotomy, she underwent another three courses of chemotherapy of the same regimen, and is showing no evidence of disease.

CONCLUSION:

Paclitaxel and carboplatin may be effective in treating mucinous cystadenocarcinoma of the ovary.

• Authors: Y Yokoyama, H Kaji, H Kondoh, E Takeuchi, Y Yamasaki, Y Inui
• Journal: Gynecologic and obstetric investigation (Gynecol Obstet Invest) Vol. 52 Issue 3 Pg. 210-4 ( 2001) ISSN: 0378-7346 [Print] Switzerland
• PMID: 11598367 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright 2001 S. Karger AG, Basel

Chemical References

• Carboplatin
• Paclitaxel

Topics

• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Carboplatin (administration & dosage)
• Cystadenocarcinoma, Mucinous (drug therapy, pathology, surgery)
• Disease-Free Survival
• Female
• Humans
• Middle Aged
• Neoplasm Staging
• Ovarian Neoplasms (drug therapy, pathology, surgery)
• Paclitaxel (administration & dosage)