Two cases of pseudoaldosteronism (Liddle's syndrome) in siblings.

Abstract	Two cases of Liddle's syndrome were found in a brother and sister. Both showed typical hypokalemic hypertension without hyperaldosteronism. These cases showed similar responses in various pharmacological tests and their symptoms of hypokalemic and hypertension were relieved by triamterene. And in a family survey, the father appeared to be affected. This seems to be the first report on this syndrome in Japan.
Authors	F Ono, H Harada, K Komatsu, K Saijo, K Miyoshi
Journal	Endocrinologia japonica (Endocrinol Jpn) Vol. 22 Issue 2 Pg. 163-7 (Apr 1975) ISSN: 0013-7219 [Print] Japan
PMID	1149690 (Publication Type: Journal Article)
Chemical References	Spironolactone Dexamethasone Triamterene
Topics	Adolescent Blood Pressure Dexamethasone (therapeutic use) Diagnosis, Differential Female Humans Hyperaldosteronism (diagnosis, drug therapy, genetics) Hypertension (complications) Hypokalemia (complications) Male Pedigree Spironolactone (therapeutic use) Triamterene (therapeutic use)

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