Abstract | OBJECTIVE: METHODS: RESULTS: Antenatal steroids were associated with significantly less periventricular leukomalacia or intraventricular hemorrhage (23% versus 31%, P =.005), periventricular leukomalacia with intraventricular hemorrhage (5% versus 11%, P =.001), and isolated periventricular leukomalacia (3% versus 7%, P =.009). Logistic regression analysis of antenatal steroid treatment, controlling for confounding maternal and neonatal characteristics, indicated that neonates treated with antenatal steroids had a 56% lower likelihood of periventricular leukomalacia with intraventricular hemorrhage (adjusted odds ratio [OR] 0.44, 95% confidence interval [CI] 0.25, 0.77) and a 58% lower likelihood of isolated periventricular leukomalacia (adjusted OR 0.42, 95% CI 0.20, 0.88). CONCLUSION:
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Authors | J C Canterino, U Verma, P F Visintainer, A Elimian, S A Klein, N Tejani |
Journal | Obstetrics and gynecology
(Obstet Gynecol)
Vol. 97
Issue 1
Pg. 135-9
(Jan 2001)
ISSN: 0029-7844 [Print] United States |
PMID | 11152922
(Publication Type: Journal Article)
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Chemical References |
- Glucocorticoids
- Betamethasone
|
Topics |
- Betamethasone
(therapeutic use)
- Glucocorticoids
(therapeutic use)
- Humans
- Infant, Newborn
- Infant, Premature
- Infant, Premature, Diseases
(prevention & control)
- Leukomalacia, Periventricular
(prevention & control)
- Logistic Models
- Retrospective Studies
- Treatment Outcome
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