Pancreatic inflammation, apoptosis, and growth: sequential events after partial pancreatectomy in pigs.

Abstract

Positive signs of pancreas regeneration were observed in rats after induced pancreatitis and partial pancreatectomy (1,2). Although the human pancreas did not regenerate after partial anatomic resection (3), the pig pancreas exhibited growth responses to bombesin after partial pancreatectomy (4). This study was undertaken to establish the time course of pancreatic inflammation, apoptosis, and hypertrophy and/or hyperplasia after partial pancreatectomy in pigs.

• Authors: J Morisset, S Morisset, K Lauzon, S Côté, J Lainé, J Bourassa, M Lessard, V Echavé
• Journal: Pancreas (Pancreas) Vol. 21 Issue 3 Pg. 321-4 (Oct 2000) ISSN: 0885-3177 [Print] United States
• PMID: 11039478 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• DNA
• Mitogen-Activated Protein Kinase 1
• Mitogen-Activated Protein Kinase 3
• Mitogen-Activated Protein Kinases

Topics

• Animals
• Apoptosis
• DNA (analysis)
• Enzyme Activation
• Female
• Hyperplasia
• Kinetics
• Mitogen-Activated Protein Kinase 1 (metabolism)
• Mitogen-Activated Protein Kinase 3
• Mitogen-Activated Protein Kinases (metabolism)
• Pancreas (pathology, physiopathology)
• Pancreatectomy
• Pancreatitis
• Regeneration
• Swine