Abstract | OBJECTIVE: To review the association between major causes of maternal mortality and vitamin A, trying to determine if these associations are causal in nature, and to highlight possible biological pathways that may explain vitamin A effects. DESIGN: Literature review, observational studies and clinical trials. The strength of association was determined by applying Bradford Hill criteria of causality. RESULTS: CONCLUSIONS: Plausible biomedical pathways can only be constructed for obstetric haemorrhage, anaemia in pregnancy, hypertension in pregnancy and pregnancy-related infections. A 40% reduction in the maternal mortality ratio, as observed in Nepal, is unlikely to be solely explained through the aforementioned pathways.
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Authors | H Faisel, R Pittrof |
Journal | Public health nutrition
(Public Health Nutr)
Vol. 3
Issue 3
Pg. 321-7
(Sep 2000)
ISSN: 1368-9800 [Print] England |
PMID | 10979152
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Anemia
(prevention & control)
- Cause of Death
- Dietary Supplements
- Dystocia
(prevention & control)
- Female
- Hemorrhage
(prevention & control)
- Humans
- Hypertension
(prevention & control)
- Maternal Mortality
- Pregnancy
- Pregnancy Complications
(mortality, prevention & control)
- Pregnancy Complications, Infectious
(prevention & control)
- Vitamin A
(administration & dosage)
- Vitamin A Deficiency
(complications)
- beta Carotene
(administration & dosage)
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