Abstract |
Using an organ bath model with porcine cavernosal tissue strips and an in vivo monkey model we demonstrated that abanoquil, a novel alpha adrenoceptor antagonist, is able to relax contracted tissue strips and induce erectile response when injected intracorporally. The erectile response in the monkeys was not dose-related and compared to the effect of papaverine injections, abanoquil induced a lower level of tumescence and rigidity. Hence, abanoquil might be useful as a facilitator of erection in the pharmacological treatment of erectile dysfunction. International Journal of Impotence Research (2000) 12, Suppl 1, S37-S40
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Authors | A Giraldi, M Wyllie, G Wagner |
Journal | International journal of impotence research
(Int J Impot Res)
Vol. 12
Issue S1
Pg. S37-S40
(Mar 2000)
ISSN: 1476-5489 [Electronic] England |
PMID | 10849564
(Publication Type: Journal Article)
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