Abstract | OBJECTIVES: METHODS: RESULTS: Mean seminal catalase-like activity (+/-SEM) in fertile men was not significantly different from that of infertile men (369 +/- 49 versus 326 +/- 17 U/mL, respectively). Mean SOD-like activity in the semen of infertile men was significantly greater than in the semen of fertile controls (46.7 +/- 1.5 versus 37.0 +/- 2.8 U/mL, respectively, P <0.05). CONCLUSIONS: Our data show that infertile men do not have deficient seminal plasma SOD- and/or catalase-like activity (two key antioxidants). These findings suggest that the high semen ROS levels in some infertile men are likely due to excessive generation of ROS rather than deficient ROS scavenging activity in semen.
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Authors | A Zini, K Garrels, D Phang |
Journal | Urology
(Urology)
Vol. 55
Issue 6
Pg. 922-6
(Jun 2000)
ISSN: 0090-4295 [Print] United States |
PMID | 10840110
(Publication Type: Journal Article)
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Chemical References |
- Reactive Oxygen Species
- Catalase
- Superoxide Dismutase
|
Topics |
- Adult
- Catalase
(metabolism)
- Humans
- Infertility, Male
(enzymology)
- Male
- Oligospermia
(enzymology)
- Reactive Oxygen Species
(metabolism)
- Semen
(chemistry, enzymology)
- Superoxide Dismutase
(metabolism)
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