HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[A case of biloma caused by early complications of hepatic artery infusion chemotherapy].

Abstract
We report a 70-year-old male who had biloma as an early complication of hepatic artery infusion chemotherapy. The patient had a history of subtotal gastrectomy for a advanced gastric cancer. Two years after the primary operation on the stomach, a solitary metastatic liver tumor was indicated by follow-up abdominal CT, and a segmental hepatectomy was performed. Soon after the hepatectomy, intraarterial catheter placement was performed via the left subclavian artery for preventive chemotherapy. Infusion chemotherapy of 10.5 g 5-FU and 75 mg CDDP was administered for a month, during which time the patient had liver dysfunction, fever, tenderness, and abdominal fullness. Abdominal CT revealed a large low density mass at a lateral segment of the liver which could not be seen on the previous CT image. Also, extravasation of contrast media was identified by angiography via the reservoir catheter. Using an interventional technique, percutaneous transhepatic drainage for biloma and extubation of the reservoir catheter were performed. The present case is thought to be of an early and rare complication of hepatic artery infusion chemotherapy. The etiology is discussed herein.
AuthorsO Miyazaki, M Hayakawa, S Nosaka, K Baba, S Iida, Y Imanishi, T Enomoto, A Ihara, I Tanaka, M Hagiwara
JournalGan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 27 Issue 5 Pg. 749-52 (May 2000) ISSN: 0385-0684 [Print] Japan
PMID10832446 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Cisplatin
  • Fluorouracil
Topics
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Bile
  • Cisplatin (administration & dosage)
  • Fluorouracil (administration & dosage)
  • Hepatectomy
  • Hepatic Artery
  • Humans
  • Infusion Pumps, Implantable (adverse effects)
  • Infusions, Intra-Arterial (adverse effects)
  • Liver Neoplasms (drug therapy, secondary)
  • Male
  • Stomach Neoplasms (pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: